Poor design rather than poor performance or analysis is generally the main reason behind scientific studies unable to deliver the expected results. Put it simply: if we are asking the wrong questions, it is impossible to get the right answers. A detailed and sophisticated study design is the backbone of the hypothesis –> experimentation –> judgment –> conclusion process. After clarifying the objectives and identifying potential errors, we provide assistance in outlining research strategy and workflow (overall workflow management, clinical site-specific, wet and dry lab site-specific, etc.) and prepare a specialized domain model – with a detailed flow chart of sites, activities, entities, their attributes and relationships.