The suite allows the genetic characterization of malignancies and the establishment of genetics-tailored therapeutic modalities – contributing to a better understanding of cancer biology. The suite is based on modules – created to answer specific questions. The modules can be customized according to the individual characteristics of the project.
Mutation Analysis Module
The module combines expression analysis, variant detection, annotation and function prediction to help the researcher identify molecular alterations behind the phenotype transformation. Module components:
Expression Analysis
Variant Calling
Variant Filtering (e.g. missense coding)
Filtering against public genetic variation databases
Annotation
Pathway analysis
Phenotype Prediction
Cancer Evolution Analysis Module
Parallel discovery of the individual germ-line or somatic cell, the primary cancer and the metastasis genotype – revealing genetic alterations behind the cancer evolution sequence. Module components: